Rise of Joint Genesis
Joint Genesis has rapidly ascended to prominence as a game-changing supplement designed to combat the challenges of age-related joint discomfort.
Rooted in the remarkable dietary habits of the elderly residents of Yuzurihara, Japan, known for their youthful joint functionality well into advanced age, Joint Genesis focuses on addressing the critical loss of hyaluronan within our joints that occurs as we age.
Scientific Foundation and Development
This innovative approach is spearheaded by Dr. Mark Weis, M.D., and the dedicated team at BioDynamix®, who have meticulously developed this formula by integrating four dynamic nutrients with Mobilee®.
This patented ingredient is scientifically verified to amplify hyaluronan levels in the joints by an impressive tenfold, offering a powerful solution for rehydrating synovial fluid and enhancing overall joint health.
Community Reception and Impact
The introduction of Joint Genesis to the market has been met with widespread acclaim, especially among the senior community across the United States.
A multitude of users have shared their transformative experiences, noting marked improvements in joint flexibility and comfort.
These enhancements have significantly impacted their daily lives, enabling them to perform activities that were once hindered by joint pain with newfound ease and without discomfort.
Clinical Validation
The effectiveness of Joint Genesis is further reinforced by extensive clinical trials, which have highlighted the extraordinary benefits of key components such as Mobilee® and French maritime pine bark in fostering joint health.
Manufacturing Excellence
BioDynamix®’s commitment to excellence is evident in their rigorous production standards. Joint Genesis is manufactured in a facility that adheres to the stringent guidelines of the FDA and cGMP, ensuring that each batch meets the highest quality benchmarks.
Inclusive Formulation
Additionally, the formulation of Joint Genesis has been thoughtfully designed to accommodate a broad spectrum of dietary preferences and restrictions, being devoid of gluten, dairy, and GMOs.
This inclusivity, combined with special pricing offers, makes Joint Genesis an accessible option for those seeking to nurture their joint health.
A Blend of Tradition and Science
What sets Joint Genesis apart is not merely its innovative formula but also its solid foundation in scientific research.
This pioneering product offers a beacon of hope for seniors eager to preserve their mobility and enhance their quality of life, embodying a synergistic blend of tradition and science.
As Joint Genesis continues to gain traction, it stands as a testament to the potential of integrating natural ingredients with cutting-edge research to address the age-old issue of joint health.
A New Era in Joint Care
In essence, Joint Genesis is not just a supplement; it represents a new era in the pursuit of maintaining youthful joint functionality.
It offers a holistic approach to joint care, promising a future where age does not dictate one’s mobility or zest for life.
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Scientific References
Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report. March 10, 2017. Vol. 66. No. 9.
Sawitzke AD, Shi H, Finco MF, Dunlop DD, Bingham CO 3rd, Harris CL, Singer NG, Bradley JD, Silver D, Jackson CG, Lane NE, Oddis CV, Wolfe F, Lisse J, Furst DE, Reda DJ, Moskowitz RW, Williams HJ, Clegg DO. The effect of glucosamine and/or chondroitin sulfate on the progression of knee OA: a report from the glucosamine/chondroitin arth intervention trial. Arth Rheum. 2008 Oct;58 (10):3183-91. doi: 10.1002/art.23973.
Ian J. Wallace, Steven Worthington, David T. Felson, Robert D. Jurmain, Kimberly T. Wren, Heli Maijanen, Robert J. Woods, and Daniel E. Lieberman. Knee OA has doubled in prevalence since the mid-20th century. Anthropology. August 14, 2017. doi.org/10.1073/
Tamer TM. Hyaluronan and synovial joint: function, distribution and healing. Interdiscip Toxicol. 2013;6(3):111-125. doi:10.2478/intox-2013-0019
Necas, J., Bartosikova, L., Brauner, P., & Kolar, J. (2008). Hyaluronic acid (hyaluronan): A review. Veterinarni Medicina, 53(8), 397–411. doi.org/10.17221
Ingram KR, Wann AK, Angel CK, Coleman PJ, Levick JR. Cyclic movement stimulates hyaluronan secretion into the synovial cavity of rabbit joints. J Physiol. 2008;586(6):1715-1729. doi:10.1113/jphysiol.2007.146753
J R Levick. Physiology, Basic Medical Sciences, St. George’s Hospital Medical School, Hyaluronan, the guardian of joints. Physiology News Magazine. [2007]. Issue 67. doi.org/10.36866/pn.67.18
Oe, M., Tashiro, T., Yoshida, H. et al. Oral hyaluronan relieves knee pain: a review. Nutrition Journal 15, 11 (2015). doi.org/10.1186/s12937-016-0128-2
Jung H. Hyaluronidase: An overview of its properties, applications, and side effects. Arch Plast Surg. 2020;47(4):297-300. doi:10.5999/aps.2020.00752
Temple-Wong MM, Ren S, Quach P, et al. Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration. Arth Res Ther. Published 2016 Jan 21. doi:10.1186/s13075-016-0922-4
Nicholls MA, Fierlinger A, Niazi F, Bhandari M. The Disease-Modifying Effects of Hyaluronan in the OA Disease State. Clin Med Insights Arth Musculoskelet Disord. 2017. doi:10.1177/1179544117723611
Tashiro T, Seino S, Sato T, Matsuoka R, Masuda Y, Fukui N. Oral administration of polymer hyaluronic acid alleviates symptoms of knee OA: a double-blind, placebo-controlled study over a 12-month period. Scientific World Journal. 2012. doi: 10.1100/2012/167928.
Möller I, Martinez-Puig D, Chetrit C. Oral administration of a natural extract rich in hyaluronic acid for the treatment of knee OA with synovitis: a retrospective cohort study. Clinical Nutrition Supplements 2009.
Douglas S Kalman, Maria Heimer, Anita Valdeon, Howard Schwartz and Eric Sheldon. Effect of a natural extract of chicken combs with a high content of hyaluronic acid on pain relief and quality of life in subjects with knee OA: a pilot randomized double-blind placebo-controlled trial. Nutrition Journal 2008
Martinez-Puig D, Möller I, Fernández C, Chetrit C. Efficacy of oral administration of yoghurt supplemented with a preparation containing hyaluronic acid (Mobilee™) in adults with mild joint discomfort: a randomized, double-blind, placebo controlled intervention study. Mediterranean Journal of Nutrition and Metabolism 2013;6:63–68.
Sánchez J, Bonet ML, Keijer J, van Schothorst EM, Mölller I, Chetrit C, Martinez-Puig D, Palou A. Blood cell transcriptomics as a source of biomarkers of articular health. Annals of Nutrition and Metabolism 2013;63(S1):538
Moriña D, Solà R, Valls RM, López de Frutos V, Montero M, Giralt M, Papell I, Bernal G, Faba J, Casajuana C, Rodríguez A, Chetrit C, Martinez-Puig, Efficacy of a Low-fat Yogurt Supplemented with a Rooster Comb Extract on Joint Function in Mild Knee Pain Patients: A Subject-level Meta-analysis. Annals of Nutrition and Metabolism 2013;63(S1):1386
Rohdewald PJ. Review on Sustained Relief of OA Symptoms with a Proprietary Extract from Pine Bark. J Med Food. 2018;21(1):1-4. doi:10.1089/jmf.2017.0015
Cisár P, Jány R, Waczulíková I, Sumegová K, Muchová J, Vojtassák J, Duraćková Z, Lisý M, Rohdewald P. Effect of pine bark extract on symptoms of knee OA. Phytother Res. 2008 Aug;22(8):1087-92. doi: 10.1002/ptr.2461.
Mulek et al. “Distribution of Constituents and Metabolites of Maritime Pine Bark Extract into Serum, Blood Cells, and Synovial Fluid of Patients with Severe OA: A Randomized Controlled Trial”. Nutrients. 2017. Doi:10.3390/nu9050443
Rohdewald, Peter Jörg. “Review on Sustained Relief of OA Symptoms with a Proprietary Extract from Pine Bark.” Journal of Medicinal Food. V 21,1 (2018): 1-4. doi:10.1089/jmf.2017.0015
Cisár P, Jány R, Waczulíková I, Sumegová K, Muchová J, Vojtassák J, Duraćková Z, Lisý M, Rohdewald P. Effect of pine bark extract on symptoms of knee OA. Phytother Res. 2008 Aug;22(8):1087-92. doi: 10.1002/ptr.2461.
Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with OA. Arthr Rheum. 2001 Nov;44(11):2531-8. doi: 10.1002/1529-0131 (200111)
Mashhadi NS, Ghiasvand R, Askari G, Hariri M, Darvishi L, Mofid MR. Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidence. Int J Prev Med. 2013;4(Suppl 1):S36–S42.
Bartels EM, Folmer VN, Bliddal H, Altman RD, Juhl C, Tarp S, Zhang W, Christensen R. Efficacy and safety of ginger in OA patients: a meta-analysis of randomized placebo-controlled trials. OA Cartilage. 2015 Jan;23(1):13-21. doi: 10.1016/j.joca.2014.09.024.
Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for OA patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020 Jul 17;20(1):225. doi: 10.1186/s12906-020-02985-6.
Siddiqui MZ. Boswellia serrata, a potential anti-inflammatory agent: an overview. Indian J Pharm Sci. 2011 May;73(3):255-61. doi: 10.4103/0250-474X.93507.